Responsive mage

Dall'Aglio Lorenza

Erasmus Medical Center NA-29, · l.dallaglio@erasmusmc.nl

PhD fellow conducting empirical research on the neurobiology of mental health problems in childhood and adolescence (i) to identify biotypes of disorders based on brain structure and connectivity with machine learning approaches and, (ii) based on repeated measurements, to characterize brain and symptom developmental trajectories


Education

PhD fellow in Population Neuroimaging

Collaboration project Erasmus MC and Harvard, Netherlands and USA
Supervision: Prof. Henning Tiemeier (Harvard and Erasmus MC, Promoter), Dr. Ryan Muetzel (Erasmus MC), Dr. Tonya White (Erasmus MC)

  • Investigating the relationship between mental health problems and neurobiology in childhood and adolescence by leveraging machine learning algorithms and longitudinal modelling, in Generation R and ABCD
  • Quality control of FreeSurfer output (involvement in training and rating), incidental findings check on brain scans (T1, T2, rsfMRI), performing MRI scans (sMRI, DTI, rsfMRI)
  • Oct 2019 - Present Responsive mage Responsive mage

    MSc in Epidemiology

    Netherlands Institute for Health Sciences, Netherlands

    Acquiring training in epidemiological methods, biostatistics, and programming languages

    Oct 2019 - Present

    MSc in Behavioral Genetics

    King's College London, UK

  • Graduated with Distinction (A+)
  • Thesis: Supervised by Prof. Cathryn Lewis and Dr. Oliver Pain, "The Genetic Component of Gene Expression in Major Depression: A Transcriptome-Wide Association Study” (grade: A+)
  • Performed quantitative and molecular genetic analyses in R and Bash, including twin modelling (OpenMx), GWASs (PLINK), polygenic risk score calculations (PRSice)
  • Learned laboratory techniques such as DNA extraction, quantification and PCR
  • Acquired knowledge of the biological (-omics) and environmental factors involved in the etiology of mental health disorders
  • Sep 2018 - Sep 2019

    BSc in International Psychology

    Erasmus University Rotterdam, Netherlands

  • Graduated with 8.4/10
  • Thesis supervised by Dr. Ruth Van Der Hallen: “The role of DNA methylation and histone modifications in Autism Spectrum Disorder and Attention-Deficit/Hyperactivity Disorder” (grade: 9.5/10).
  • Modules included Biological, Clinical and Developmental Psychology, Statistics, Scientific Writing and Presentation Skills

  • Aug 2015 - July 2018

    Publications

    Dall’Aglio L., Muka T., Cecil C.A.M., Bramer W.M., Verbiest M.P.J., Nano J., Cortes Hildalgo A., Franco O.H. & Tiemeier H. (2018). The role of epigenetic modifications in neurodevelopmental disorders: A systematic review. Neuroscience & Biobehavioral Reviews, 94, 17-30. https://doi.org/10.1016/j.neubiorev.2018.07.011


    Work Experience

    Research Trainee in the Generation R Department

    Erasmus Medical Center, Netherlands

  • Supervision: Dr Charlotte AM Cecil (Erasmus MC, King’s College London), Dr Jolien Rijlaarsdam (Erasmus MC), Prof. Henning Tiemeier (Harvard and Erasmus MC)
  • Conducted, as first author, empirical research on DNA methylation and maternal care
  • Performed latent variable modelling and epigenetic analyses (DMP, DMR, candidate gene follow-up) through R (packages: lavaan, cgpassoc, dmrff)
  • Nov 2017 - Sep 2019

    Language Teacher (Italian)

    Erasmus Language Sharing, Netherlands

  • Designed teaching materials
  • Fostered presentation skills by teaching groups of ~10 University students
  • Apr - Dec 2017

    Research Intern in Psychiatric Epidemiology

    Erasmus Medical Center, Netherlands

  • Supervision: Prof. Henning Tiemeier (Harvard and Erasmus MC), Dr. Charlotte Cecil (Erasmus MC, King’s College London), Dr. Taulant Muka (Erasmus MC)
  • Conducted, as first author, a systematic review on the role of DNA methylation and histone modifications in ASD and ADHD published in Neuroscience & Biobehavioral Reviews
  • Participation in the 10th DOHaD World Congress.
  • Nov 2016 - Nov 2017

    Substitute Tutor of Psychology

    Erasmus University Rotterdam, Netherlands

  • Supervised tutorial group meetings of ~12 University students, ensuring appropriate discussion and elaboration on the course materials.
  • Mar - July 2017

    Technical Skills

    Quantitative Data Analysis
    R
  • Python SPSS
  • Qualitative Data Analysis
    Qiqqa Atlas.ti
    Reference Managers
    Zotero Endnote
  • Mendeley

  • Additional Projects

    Together with Elisabet Blok and Samuel Westwood, I am a co-founder of the Rotterdam R.I.O.T. Science Club, a scientific community providing training on how to perform Reproducible, Interpretable, Open, Transparent Science. Seminars occur monthly and are open to scientists, students, clinicians, as well as the public. The Rotterdam RIOTs are a collaboration with King's College London, where the RIOT science club was funded by Dr Westwood, and are now part of the Open Science Community in Rotterdam (OSCR). Find out more by clicking below!


    Awards

    • Peter McGuffin Prize Scholarship (£4,950), King's College London, UK
    • Best Bachelor Thesis of the Psychology program, Erasmus University Rotterdam, Netherlands
    • Selected for the Personal Leadership Program of Erasmus University Rotterdam, Netherlands
    • Selected for the Honor Program of Erasmus University Rotterdam, Netherlands (10% admission rate)

    Languages

  • Native Italian
  • Proficient English
  • Advanced French
  • Intermediate Spanish
  • Beginner Dutch